Pre-Meeting Scientific Activities

Wednesday, June 5, 2019

09.00 – 12:00  Pre-Meeting Scientific tour. Visit to three research centres located around the Barcelona Biomedical Research Park (PRBB,, which perform cutting-edge scientific research that can be relevant for further understanding the aetiology of Down syndrome.  FULLY BOOKED

  • Mesoscopic Imaging Facility at the European Molecular Biology Laboratory (EMBL). The facility houses state-of-the-art imaging services enabling scientists worldwide to access mesoscopic imaging technologies. These include Optical Projection Tomography (OPT) and Light Sheet Microscopy (SPIM), which are specifically designed for 3- and higher-dimensional studies of multi-cellular systems ranging in size up to adult rodent organs.
  • Center for Genomic Regulation (CRG). This CRG is an international biomedical research institute of excellence that has developed the ‘Stick Out Your Tongue’ (‘Saca la Lengua’) project. This is a citizen’s science project that aims to study the mouth’s microbiome and its possible relationship with our environmental characteristics and lifestyle, with specific data on Down syndrome population.
  • Barcelonaβeta Brain Research Center (BBRC)- Pasqual Maragall Foundation (FPM). The BBRC is a research center dedicated to the prevention of Alzheimer’s disease and the study of cognitive functions affected in healthy and pathological aging. It was created in 2012 by the Pasqual Maragall Foundation, and it offers researchers and collaborators three specialised facilities at the service of brain research, including neuroimaging acquisition services, a clinical trial unit, and a cognition laboratory.  




Visit a research lab investigating on Down syndrome!

Spanish PIs welcome young investigators from abroad to visit their labs around the dates of the T21RS Conference. This will allow young researchers to meet senior and junior scientists, get familiar with the laboratory’s research, facilities and techniques, to favor future exchanges and networking.


  • You are not working in a Spanish laboratory
  • You are registered at the T21RS International Conference 2019
  • You have submitted an abstract as first author to the T21RS International Conference 2019

To join the program contact: Laura Videla Toro

Explore Down syndrome research labs in Barcelona: (see the T21RS  “la Caixa” Programme for Young Investigators)

Laboratory: Alzheimer Down Unit, Hospital de la Santa Creu i Sant Pau

  • Address: Sant Antoni Mª Claret 167, 08025 Barcelona.
  • Number of participants: 4-6.
  • Date: 05 June, 2019 | One-day session.
  • Techniques: Clinical Research related to neuropsychology, biochemical biomarkers, neuroimaging.
  • Type of activity: Visit and seminar.
  • Contact person: Laura Videla (

Laboratory: Tissue Engineering Unit, Center for Genomic Regulation

  • Address: Dr. Aiguader 88, 08003 Barcelona.
  • Number of participants: 4-6.
  • Date: 05 June, 2019 | One-day session.
  • Techniques: Technologies used in the fields of stem cell biology, stem cell differentiation, organoid formation and induced pluripotent stem cells (iPSCs). The Biomolecular Screening & Protein Technologies Unit also provides CRISPR/Cas9 genome editing technology.
  • Type of activity: Visit to the Unit. Selected participants will get an overview of the background and current methods for the generation and characterization of pluripotent stem cells, primordial germ cells, organoids and their genetic manipulation by CRISPR/Cas9 technology. They will have the opportunity to learn how to generate and characterise mouse embryonic stem cells and induced pluripotent stem cells (morula aggregation and teratoma assays), primordial germ cells, or cerebral organoids, depending on their interest.
  • Contact person: Laura Batlle (

Laboratory: Cellular and Systems Neurobiology, Center for Genomic Regulation

  • Address: Dr. Aiguader 88, 08003 Barcelona.
  • Number of participants: 4-6.
  • Date05 June, 2019 | One-day session.
  • Techniques: CLARITY, Computational Modelling, Bioimage Analysis.
  • Type of activity: Visit to the lab. Selected participants will get an overview on state-of-the-art optical tools, imaging systems, and analysis methods that are being developed for the study of neuronal circuits. The session includes theory and practice of emerging neurotechnologies and computational modelling. The students will have the opportunity to attend a demo on modified CLARITY protocol that will be used to clear whole mouse embryos or whole mouse brains, sample handling and positioning large 3D cleared brain tissue specimens and acquiring z-stacks and 3D-rendering large datasets at the SPIM.
  • Contact person: Linus Manubens (

 Laboratory: Starlab Barcelona

  • Address: Av. Tibidabo 47 bis, 08035 Barcelona.
  • Number of participants: 4-6.
  • Date: 05 June, 2019 | One-day session.
  • Techniques: Transcranial Current Stimulation (tCS) and Electrophysiological (EEG) Monitoring
  • Type of activity: Visit to the Unit. Participants will get a theoretical overview of the advanced techniques for tCS and EEG with examples of studies for cognitive enhancement and its quantification through EEG neuromarkers. They will have the opportunity to work hands-on with Neuroelectrics user-friendly and wireless systems for tCS and EEG in a demo case.
  • Contact person: Aureli Soria-Frisch ( and Marta Castellano ( Supported by Neuroelectrics.