Satellite Symposia

Thursday, June 6 , 2019

09:00 – 13:00   PRE-MEETING SATELLITE SYMPOSIA (parallel)


T21RS Committee for clinical research: Andre Strydom (King’s College London, UK) (chair)

CLINICAL SESSION 1: Health co-morbidities in older adults with Down syndrome – assessment and diagnosis

Adult clinical committee: Shahid Zaman (University of Cambridge, UK), Juan Fortea (Fundació Catalana Síndrome de Down and Hospital San Pau, SP), Wayne Silverman (Kennedy Krieger Institute and Johns Hopkins University School of Medicine, USA), Tonnie Coppus (Radboud University Medical Center, NL), Ben Handen (University of Pittsburgh, USA), Elizabeth Head (University of Kentucky, USA), Weihong Song (University of British Columbia, CA)

09:00 – 09:30   Registration / coffee
09:30 – 09:45   Welcome and Introduction. Andre Strydom (King’s College London, UK)
09:45 – 10:15   Overview of the health needs of older adults. Tonnie Coppus (Radboud University Medical Center, NL)
10:15 – 10:45   Sleep Apnea. Anne-Sophie Rebillat (Institut Jerome Lejuene, FR)
10:45 – 11:00   Break
11:00 – 11:30  Cognitive function in aging adults. Sharon Krinsky-McHale (New York State Institute for Basic Research in Developmental Disabilities, USA)
11:30 – 12:00   Dementia management and maintaining functional abilities.  (Professor Mary McCarron, Trinity college, Dublin, Ireland) 
12:00 – 12:30   Summary and discussion

CLINICAL SESSION 2: Health co-morbidities in children with Down syndrome

Child/developmental subcommittee: Stephanie Sherman (Emory University, USA) – co-chair; Stefano Vicari (Bambino Gesu’ Children’s Hospital, IT) – co-chair, Cecile Cieuta-Walti (Institut Jerome Lejuene, FR), Brain Skotko (Massachusetts General Hospital, USA), Julie Korenberg (University of Utah, USA), Silvia Sacco (Institut Jerome Lejuene, FR), Rafael de la Torre (IMIM-Hospital del Mar Medical Research Institute, SP), Jamie Edgin (University of Arizona, USA), Stefania Veltri (IT)

09:00 – 09:30  Registration / coffee
09:30 – 09:45  Welcome and Introduction. Stephanie Sherman (Emory University, USA)
09:45 – 10:15   Overview of the health needs of children with Down syndrome. Jesús Florez (Affiliation—to be confirmed)
10:15 – 10:45 Medical comorbidities of childhood and their potential impact on cognition and development. George Capone, Kennedy Krieger Institute, USA-to be confirmed)
10:45 – 11:00  Break
11:00 – 11:30 Psychiatric comorbidities of childhood/adolescents and their association with cognitive impairment.  Stefano Vicari  (Ospedale Pediatrico Bambino Gesu, IT)
11:30 – 12:00  Interventions from early childhood to adolescents–how we can help. Rafael de la Torre Fornell, (Universitat Pompeu Fabra, SP)
12:00 – 12:30  Panel: Q/A and discussion

T21RS Committee for Preclinical research: Yann Hérault (Institut de Génétique et de Biologie Moléculaire et Cellulaire, FR)(Chair), William Mobley (University of California-San Diego, USA), Elizabeth Fisher (University College London, UK), Marie-Claude Potier (ICM, FR), Stylianos Antonarakis (University of Geneva, CH), Jean-Maurice Delabar (CNRS, FR), Eugene Yu (Roswell Park Cancer Institute, USA), Katheleen Gardiner (University of Colorado, USA), Mara Dierssen (Centre for Genomic Regulation (CRG), SP), Anita Bhattacharyya (University of Wisconsin, USA), Randall Roper ((Indiana University-Purdue University Indianapolis, USA)

Mouse master class

09:00 – 09:15  Registration / coffee
09:15 – 09:45  Overview of currently available preclinical mouse models. Yann Hérault (Institut de Génétique et de Biologie Moléculaire et Cellulaire, FR)
09:45 – 10:15  Genetic quality control, maintenance and breeding procedures. Eugene Yu  (Roswell Park Cancer Institute, USA)
10:15 – 10:45  Classical behavioral phenotyping. Mara Dierssen (Centre for Genomic Regulation (CRG), SP)
10:45 – 11:00  Break
11:00 – 11:30  Craniofacial and skeletal phenotyping. Randall Roper (Indiana University-Purdue University Indianapolis, USA)
11:30 – 12:00  Electrophysiology. William Mobley (University of California-San Diego, USA)
12:00 – 12:30  Preclinical testing. Jean-Maurice Delabar (CNRS, FR)
12:30 – 13:00  Discussion on key information about models and their availability (moderated by Lizzy Fisher) and perspective on new animal models for Down syndrome research. Roger Reeves (Johns Hopkins University School of Medicine, USA) and Victor Tybulewicz (Francis Crick Institute, UK)