T21RS2019 «la Caixa» Program for Young Investigators

With the support of «la Caixa» Foundation, T21RS launches a new program for Young Researchers in Down syndrome to coincide with the 3rd T21RS conference in Barcelona. «la Caixa» Foundation will fund short stays (1 week to 1 month) for young researchers in Spanish labs before or after the T21RS meeting. Spanish PIs welcome young investigators from abroad to visit their labs around the dates of the T21RS Conference, allowing young researchers to meet senior and junior scientists, get familiar with the laboratory’s research, facilities and techniques, and to promote future collaborations and networking.

Interested researchers should contact a lab directly to set up a lab visit. The Down syndrome research labs willing to receive students are listed below, but participants can contact other labs in Spain.

Alzheimer Down Unit, Hospital de la Santa Creu i Sant Pau

  • Address: Sant Antoni Mª Claret 167, 08025 Barcelona.
  • Director: Juan Fortea
  • Techniques: Clinical Research related to neuropsychology, biochemical biomarkers, neuroimaging.
  • Contact person: Laura Videla (lvidela@santpau.cat).

Cellular and Systems Neurobiology, Center for Genomic Regulation

  • Address: Dr. Aiguader 88, 08003 Barcelona.
  • Director: Mara Dierssen
  • Techniques: Omics, Behavioral analysis, CLARITY, Computational Modelling, Bioimage Analysis.
  • Contact person: Linus Manubens (linus.manubens@crg.eu).

Neuromodulation of Neural Networks and Circuits group, Hospital del Mar Medical Research Institute

  • Address: Dr. Aiguader 88, 08003 Barcelona.
  • Host: Dr. Victoria Puig
  • Techniques: In vivo electrophysiology, mouse models of brain disease, neuropharmacology, cognitive neuroscience
  • Contact person: Victoria Puig (mpuig3@imim.es).

Laboratory of Neuropharmacology, Universitat Pompeu Fabra

  • Address: Aiguader 88, 08003 Barcelona.
  • Host: Andrés Ozaita
  • Techniques: Behavioral assessesment of mouse models, biochemical biomarkers, immunohistochemical analysis.
  • Contact person: Andrés Ozaita (andres.ozaita@upf.edu).

 Institution: Instituto de Neurociencias CSIC-UMH

Multicellular Systems Biology, European Molecular Biology Laboratory (EMBL Barcelona)

  • Address:  Dr. Aiguader 88, 08003 Barcelona
  • Director: James Sharpe
  • Techniques: Preclinical research on 3D imaging, brain and skeletal phenotyping of Down syndrome mouse models.
  • Contact person: Neus Martínez-Abadías (neus.martinez@embl.es).

Integrative Pharmacology and Systems Neurosciences Research Group, Hospital del Mar Medical Research Institute (IMIM)

  • Address: Aiguader 88, 08003 Barcelona.
  • Host: Rafael de la Torre
  • Techniques: Electrophysiological assessments of mouse models. Cognitive evaluation in clinical trials.
  • Contact person: Rafael de la Torre (rtorre@imim.es).

Dynamical Systems Biology, Universitat Pompeu Fabra

  • Address: Dr. Aiguader 88, 08003 Barcelona
  • Director: Jordi Garcia-Ojalvo
  • Techniques: Spiking network modeling, mesoscopic brain models, stochastic processes, brain networks, data assimilation
  • Contact person: Miquel Sas (miquel.sas@upf.edu)

 

The awardees will also be offered participation in the following pre-meeting sessions in Barcelona:

Alzheimer Down Unit, Hospital de la Santa Creu i Sant Pau

  • Address: Sant Antoni Mª Claret 167, 08025 Barcelona.
  • Number of participants: 4-6.
  • Date: 05 June 2019 | One-day session.
  • Techniques: Clinical Research related to neuropsychology, biochemical biomarkers, neuroimaging.
  • Type of activity: Visit and seminar.
  • Contact person: Laura Videla (lvidela@santpau.cat).

 Tissue Engineering Unit, Center for Genomic Regulation

  • Address: Dr. Aiguader 88, 08003 Barcelona.
  • Number of participants: 4-6.
  • Date: 05 June 2019 | One-day session.
  • Techniques: Technologies used in the fields of stem cell biology, stem cell differentiation, organoid formation and induced pluripotent stem cells (iPSCs). The Biomolecular Screening & Protein Technologies Unit also provides CRISPR/Cas9 genome editing technology.
  • Type of activity: Visit to the Unit. Selected participants will get an overview of the background and current methods for the generation and characterization of pluripotent stem cells, primordial germ cells, organoids and their genetic manipulation by CRISPR/Cas9 technology. They will have the opportunity to learn how to generate and characterize mouse embryonic stem cells and induced pluripotent stem cells (morula aggregation and teratoma assays), primordial germ cells, or cerebral organoids, depending on their interest.
  • Contact person: Laura Batlle (laura.batlle@crg.eu)

Cellular and Systems Neurobiology, Center for Genomic Regulation

  • Address: Dr. Aiguader 88, 08003 Barcelona.
  • Number of participants: 4-6.
  • Date05 June 2019 | One-day session.
  • Techniques: CLARITY, Computational Modelling, Bioimage Analysis.
  • Type of activity: Visit to the lab. Selected participants will get an overview on state-of-the-art optical tools, imaging systems, and analysis methods that are being developed for the study of neuronal circuits. The session includes theory and practice of emerging neurotechnologies and computational modelling. The students will have the opportunity to attend a demo on modified CLARITY protocol that will be used to clear whole mouse embryos or whole mouse brains, sample handling and positioning large 3D cleared brain tissue specimens and acquiring z-stacks and 3D-rendering large datasets at the SPIM.
  • Contact person: Linus Manubens (linus.manubens@crg.eu).

Starlab Barcelona

  • Address: Av. Tibidabo 47 bis, 08035 Barcelona.
  • Number of participants: 4-6.
  • Date: 05 June 2019 | One-day session.
  • Techniques: Transcranial Current Stimulation (tCS) and Electrophysiological (EEG) Monitoring
  • Type of activity: Visit to the Unit. Participants will get a theoretical overview of the advanced techniques for tCS and EEG with examples of studies for cognitive enhancement and its quantification through EEG neuromarkers. They will have the opportunity to work hands-on with Neuroelectrics user-friendly and wireless systems for tCS and EEG in a demo case.
  • Contact person: Aureli Soria-Frisch (aureli.soria-frisch@starlab.es) and Marta Castellano (marta.castellano@starlab.es). Supported by Neuroelectrics

 

  1. Eligibility Criteria
  • Applicant must be an excellent young scientist/clinical investigator working in the field of Down syndrome. PhD students, postdocs and early-stage PIs are eligible.
  • Applicant must be registered for T21RS and we will favor members of T21RS.
  • Applicants must be an author on a submitted T21RS2019 abstract and must participate in the Science and Society session. Presenting authors will be favored.
  • Applicant must pay all expenses of attending the conference up front, including conference registration fee, travel, accommodations and meals. Funding will be provided as a reimbursement as a check mailed to the participant approximately 6-8 weeksafter the conference. 
  1. Eligible expenses

Eligible expenses include conference registration, transportation (air or land transportation from home region to conference city in economy class), hotel room, and occupancy tax for stays from one week to one month.  In order to receive the full-awarded reimbursement, receipts for T21RS2019 registration, transportation and hotel accommodations are required. 

  1. Application

Application packages must be submitted in English and should include:

  1. Completed application form that includes brief statements by the applicant about his/her current research and the value to the applicant’s research and career goals that will be gained by visiting the host lab.
  2. Copy of the applicant’s registration and abstract submission confirmation for the T21RS2019 meeting.
  3. Applicant’s CV, including education, honors/awards, publications (abstracts and manuscripts).
  4. Acceptance email or letter from the host laboratory.

Submit application documents to Anita Bhattacharyya, bhattacharyy@waisman.wisc.edu, by May 1. 

  1. Notification

Applicants will be notified no later than May 15, 2019 of the funding status. Funded applicants will be required to present evidence of their eligibility status to receive their funds, and must sign in with the Registration Desk to record their attendance. In all cases, funds will be mailed to funded applicants after the conference.

Upon acceptance, the awardee will be expected to:

  1. Write a short piece on the experience in lay terms (3-5 pages) for the T21RS bulletin.
  2. Be available for an interview (by video or in person).
  3. Participate in the Science and Society session of the T21RS conference.